{"product_id":"盐酸司美那非片-onvita-simenafil-hydrochloride-tablets-5mg-5tablets-for-male-erectile-dysfunctioned","title":"盐酸司美那非片, Simenafil Hydrochloride Tablets, 5mg*5 Tablets, for Male Erectile Dysfunction(ED)","description":"\u003ch1\u003eOnvita® Simenafil Hydrochloride Tablets\u003c\/h1\u003e\n\u003ch2\u003eBasic Product Information\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eBrand Name:\u003c\/strong\u003e Onvita® (昂伟达) \u003cbr\u003e\u003cstrong\u003eGeneric Name\u003c\/strong\u003e: Simenafil Hydrochloride Tablets \u003cbr\u003e\u003cstrong\u003eActive Ingredient\u003c\/strong\u003e: Simenafil Hydrochloride \u003cbr\u003e\u003cstrong\u003eStrengths\u003c\/strong\u003e: 5 mg\u003cbr\u003e\u003cstrong\u003eDrug Category\u003c\/strong\u003e: Highly selective phosphodiesterase type 5 (PDE5) inhibitor \u003cbr\u003e\u003cstrong\u003eApproval Background\u003c\/strong\u003e: Class 1 innovative drug, jointly developed by Shanghai Institute of Materia Medica, Chinese Academy of Sciences and Suzhou Vigonvita Life Sciences. Approved by the National Medical Products Administration (NMPA) for marketing in China in July 2025. \u003cbr\u003e\u003cstrong\u003eIndication\u003c\/strong\u003e: For the treatment of male erectile dysfunction (ED).\u003c\/p\u003e\n\u003ch2\u003eMechanism of Action\u003c\/h2\u003e\n\u003cp\u003eSimenafil selectively inhibits phosphodiesterase type 5 (PDE5), relaxes the smooth muscle of the penile corpus cavernosum and increases local blood flow. Erection can only be achieved with sexual stimulation. This product is not an aphrodisiac, and no erection will occur without sexual stimulation.\u003c\/p\u003e\n\u003ch2\u003eProduct Features\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eNovel chemical structure with high PDE5 selectivity. Onset of action approximately 30 minutes after oral administration; half-life of 8–11 hours for stable sustained therapeutic effect.\u003c\/li\u003e\n\u003cli\u003eLow initial therapeutic dose: the recommended starting dose is 2.5 mg.\u003c\/li\u003e\n\u003cli\u003eFavourable safety profile. In clinical trials, this product weakly inhibits PDE6 and PDE11; no cases of visual disturbance, back pain or myalgia were observed in trials. Common adverse reactions such as headache, facial flushing and dyspepsia are mild and transient with a lower incidence than other PDE5 inhibitors.\u003c\/li\u003e\n\u003cli\u003ePharmacokinetics are basically unaffected under moderate alcohol intake (heavy alcohol consumption is not recommended).\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eDosage and Administration (Summary, please refer to the package insert for full details)\u003c\/h2\u003e\n\u003cp\u003eFor on-demand use. The recommended starting dose is 2.5 mg. The dose may be adjusted to 5 mg or 10 mg by a doctor according to therapeutic response and tolerability. Take approximately 30 minutes before sexual activity, maximum once per day.\u003c\/p\u003e\n\u003ch2\u003eContraindications\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eContraindicated in patients allergic to any ingredient of this product.\u003c\/li\u003e\n\u003cli\u003eMust not be taken together with nitrate medicines (e.g. nitroglycerin, isosorbide mononitrate). Combined use may cause severe hypotension, which can be life-threatening.\u003c\/li\u003e\n\u003cli\u003eContraindicated for women, children and adolescents under 18 years old.\u003c\/li\u003e\n\u003cli\u003eMust not be co-administered with guanylate cyclase stimulators (e.g. riociguat), which may lead to symptomatic hypotension.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eStorage and Shelf Life\u003c\/h2\u003e\n\u003cp\u003eStore sealed below 30°C. Keep out of reach of children. The shelf life is shown on the outer packaging box.\u003c\/p\u003e","brand":"Meds of China","offers":[{"title":"1 Box","offer_id":58471644528943,"sku":"昂伟达-盐酸司美那非片-5mg*5粒-1盒","price":99.0,"currency_code":"USD","in_stock":true},{"title":"3 Boxes","offer_id":58471644561711,"sku":"昂伟达-盐酸司美那非片-5mg*5粒-3盒","price":259.0,"currency_code":"USD","in_stock":true},{"title":"5 Boxes","offer_id":58471644594479,"sku":"昂伟达-盐酸司美那非片-5mg*5粒-5盒","price":399.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/2853\/1503\/files\/Yansuan_Simeinafei_Pian_1.jpg?v=1789488142","url":"https:\/\/medsofchina.com\/products\/%e7%9b%90%e9%85%b8%e5%8f%b8%e7%be%8e%e9%82%a3%e9%9d%9e%e7%89%87-onvita-simenafil-hydrochloride-tablets-5mg-5tablets-for-male-erectile-dysfunctioned","provider":"Meds of China","version":"1.0","type":"link"}